CBC-olie informatie
CBC is one of the four main cannabinoids produced by the cannabis plant. This substance is not well known to most cannabis connoisseurs, but science points to beneficial possibilities.
Cannabis is a plant that is very chemically diverse. The buds of the plant produce different types of terpenes, flavonoids and cannabinoids. Many of these substances have been scientifically proven to have medicinal potential. Cannabinoids in particular are interesting and effective. Researchers have already identified more than 100 of these components in the cannabis plant. THC and CBD are the best known of these chemicals. However, as more and more research takes place, attention is slowly shifting towards other cannabinoids.
WHAT IS CBC?
One of those cannabinoids is cannabichromene (CBC). This substance is relatively unknown. However, limited research already shows that CBC offers significant medicinal potential. Despite its low concentration, it is considered one of the four most important cannabinoids in cannabis. The cannabinoid shows structural similarities to THC, THCV, CBD and CBN.
What Is CBC
CBC occurs in high concentrations in a number of Indian landraces. Most modern Western strains are not bred for their CBC content. Partly because this cannabinoid hasn't received much attention. Moreover, we know that CBC is quite vulnerable and easily converts into the cannabinoid cannabicyclol (CBL) under the influence of heat and light.
BIOSYNTHESIS OF CBC
CBC has the same origin as THC and CBD. The existence of these cannabinoids begins with the precursor cannabigerolic acid (CBGA). Enzymes in the plant change CBGA into CBCA. The plant then converts this into CBC under the influence of heat and light.
Biosynthesis Of CBC
Most of the effects of the cannabinoid THC are mediated by interaction with receptors of the endocannabinoid system. This concerns the CB1 and CB2 receptors. However, CBC does not bind well to cannabinoid receptors. This cannabinoid has an effect by interacting with vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1).
Will CBC Play a Role in Cannabis Medicine in the Future?
These receptors, also known as transient receptor potential channels (TRP channels), are located on the plasma membrane of various cell types. They mediate various physical sensations, such as pain, temperature, taste, pressure and vision.
The influence of CBC on TRP channels ensures an increased level of anandamide. This is a cannabinoid that is naturally present in the body. Anandamide is similar in structure to THC and interacts with receptors. It provides a better mood and the well-known 'runner's high'.
CURRENT SCIENTIFIC RESEARCH ON CBC
The CBC substance is not well known to most cannabis connoisseurs, but science points to beneficial possibilities.
CBC POTENTIALLY WORKS WITH OTHER CANNABINOIDS
CBC Potentially Interacts With Other Cannabinoids
CBC may also interact with other cannabinoids. However, little research has been done in this area. Nevertheless, the so-called entourage effect shows that certain terpenes and cannabinoids may work together in a synergistic manner. And that strengthens the mutual effects. However, we do not yet know whether CBC has synergy with other cannabinoids, but due to its potential medicinal effect, the chance of this is high.
CBC AND BRAIN FUNCTION
CBC And Brain Function
Neurological disorders, such as Alzheimer's, are becoming increasingly common. Therefore, the need to find effective medication is great. CBC shows promise in this area, but more clinical research is needed to confirm its effects.
Research from 2013 with mouse cells shows that various cannabinoids, including CBC, have clear positive effects on the viability of neural stem cells. These cells are crucial for brain plasticity under normal physiological conditions, but also after brain injury.
These cells are capable of differentiating into three other cell types: astrocytes, neurons and oligodendrocytes. Of these, astrocytes are important in the physical and metabolic support of the brain. They play an important role in homeostasis of the brain. However, they are also related to Alzheimer's disease. CBC may be able to prevent neural stem cells from differentiating into astrocytes, thus exerting a pro-neurogenic effect.
Cannabis is a plant that is very chemically diverse. The buds of the plant produce different types of terpenes, flavonoids and cannabinoids. Many of these substances have been scientifically proven to have medicinal potential. Cannabinoids in particular are interesting and effective. Researchers have already identified more than 100 of these components in the cannabis plant. THC and CBD are the best known of these chemicals. However, as more and more research takes place, attention is slowly shifting towards other cannabinoids.
WHAT IS CBC?
One of those cannabinoids is cannabichromene (CBC). This substance is relatively unknown. However, limited research already shows that CBC offers significant medicinal potential. Despite its low concentration, it is considered one of the four most important cannabinoids in cannabis. The cannabinoid shows structural similarities to THC, THCV, CBD and CBN.
What Is CBC
CBC occurs in high concentrations in a number of Indian landraces. Most modern Western strains are not bred for their CBC content. Partly because this cannabinoid hasn't received much attention. Moreover, we know that CBC is quite vulnerable and easily converts into the cannabinoid cannabicyclol (CBL) under the influence of heat and light.
BIOSYNTHESIS OF CBC
CBC has the same origin as THC and CBD. The existence of these cannabinoids begins with the precursor cannabigerolic acid (CBGA). Enzymes in the plant change CBGA into CBCA. The plant then converts this into CBC under the influence of heat and light.
Biosynthesis Of CBC
Most of the effects of the cannabinoid THC are mediated by interaction with receptors of the endocannabinoid system. This concerns the CB1 and CB2 receptors. However, CBC does not bind well to cannabinoid receptors. This cannabinoid has an effect by interacting with vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1).
Will CBC Play a Role in Cannabis Medicine in the Future?
These receptors, also known as transient receptor potential channels (TRP channels), are located on the plasma membrane of various cell types. They mediate various physical sensations, such as pain, temperature, taste, pressure and vision.
The influence of CBC on TRP channels ensures an increased level of anandamide. This is a cannabinoid that is naturally present in the body. Anandamide is similar in structure to THC and interacts with receptors. It provides a better mood and the well-known 'runner's high'.
CURRENT SCIENTIFIC RESEARCH ON CBC
The CBC substance is not well known to most cannabis connoisseurs, but science points to beneficial possibilities.
CBC POTENTIALLY WORKS WITH OTHER CANNABINOIDS
CBC Potentially Interacts With Other Cannabinoids
CBC may also interact with other cannabinoids. However, little research has been done in this area. Nevertheless, the so-called entourage effect shows that certain terpenes and cannabinoids may work together in a synergistic manner. And that strengthens the mutual effects. However, we do not yet know whether CBC has synergy with other cannabinoids, but due to its potential medicinal effect, the chance of this is high.
CBC AND BRAIN FUNCTION
CBC And Brain Function
Neurological disorders, such as Alzheimer's, are becoming increasingly common. Therefore, the need to find effective medication is great. CBC shows promise in this area, but more clinical research is needed to confirm its effects.
Research from 2013 with mouse cells shows that various cannabinoids, including CBC, have clear positive effects on the viability of neural stem cells. These cells are crucial for brain plasticity under normal physiological conditions, but also after brain injury.
These cells are capable of differentiating into three other cell types: astrocytes, neurons and oligodendrocytes. Of these, astrocytes are important in the physical and metabolic support of the brain. They play an important role in homeostasis of the brain. However, they are also related to Alzheimer's disease. CBC may be able to prevent neural stem cells from differentiating into astrocytes, thus exerting a pro-neurogenic effect.